# Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal C

Source: https://onco.cc/trials/nct02885753/  
OnCo record `nct02885753` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of leucovorin (folinic acid), panitumumab, bevacizumab (glioblastoma use) and fOLFIRI (5-FU, leucovorin, irinotecan) in colorectal cancer, run by Federation Francophone de Cancerologie Digestive, now recruiting.

## Summary

Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver is a phase 3, randomised interventional study registered as NCT02885753 by Federation Francophone de Cancerologie Digestive, with a registry enrolment figure of 348 participants, started 2016-12 and due to reach its primary completion in 2028-09. Interventions recorded: Oxaliplatin intravenous; 5 FU bolus; Folinic acid; Oxaliplatin intra-arteriel; Panitumumab; Bevacizumab; 5 FU continuous; Irinotecan. Conditions listed: Colorectal Neoplasms. Primary outcome: progression-free survival. Colorectal eligibility wording from the registry: "* Histologically proven colorectal adenocarcinoma with hepatic metastasis(es)". Sites: Belgium, France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: OSCAR
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT02885753
- Phase: 3
- Setting: Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver
- Sponsor: Federation Francophone de Cancerologie Digestive
- Enrolled: 348

## Sources

- ClinicalTrials.gov NCT02885753: https://clinicaltrials.gov/study/NCT02885753

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Monoclonal antibodies](https://onco.cc/technologies/monoclonal-antibody/), [Topoisomerase-I inhibitors (and ADC payloads)](https://onco.cc/technologies/topoisomerase-inhibitors/)
- drugs: [Bevacizumab (glioblastoma use)](https://onco.cc/drugs/bevacizumab-glioma/), [FOLFIRI (5-FU, leucovorin, irinotecan)](https://onco.cc/drugs/folfiri/), [Leucovorin (folinic acid)](https://onco.cc/drugs/leucovorin/), [Panitumumab](https://onco.cc/drugs/panitumumab/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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