# A Randomized Controlled Trial of Neoadjuvant Weekly Paclitaxel Versus Weekly Paclitaxel Plus Weekly Carboplatin In Women With Large Operable or Locally Advanced

Source: https://onco.cc/trials/nct03168880/  
OnCo record `nct03168880` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of paclitaxel / nab-paclitaxel and carboplatin in triple-negative breast cancer, run by Tata Memorial Hospital, active but no longer recruiting.

## Summary

A Randomized Controlled Trial of Neoadjuvant Weekly Paclitaxel Versus Weekly Paclitaxel Plus Weekly Carboplatin In Women With Large Operable or Locally Advanced, Triple Negative Breast Cancer is a phase 3, randomised interventional study registered as NCT03168880 by Tata Memorial Hospital, with a registry enrolment figure of 720 participants, started 2010-04 and due to reach its primary completion in 2025-11-30. Interventions recorded: Paclitaxel + Carboplatin; Paclitaxel only. Conditions listed: Triple Negative Breast Cancer. Triple-negative eligibility wording from the registry: "All patients with baseline clinical staging T4, N0-3, M0 or T1-4, N2-3, M0 and T3, N1, M0 with triple negative hormone status". Sites: India. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-24
- Also known as: TNBC
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT03168880
- Phase: 3
- Setting: A Randomized Controlled Trial of Neoadjuvant Weekly Paclitaxel Versus Weekly Paclitaxel Plus Weekly Carboplatin In Women With Large Operable or Locally Advanced, Triple Negative Breast Cancer
- Sponsor: Tata Memorial Hospital
- Enrolled: 720

## Sources

- ClinicalTrials.gov NCT03168880: https://clinicaltrials.gov/study/NCT03168880

## Connected records

- cancers: [Early triple-negative breast cancer](https://onco.cc/cancers/tnbc-early/), [Metastatic triple-negative breast cancer](https://onco.cc/cancers/tnbc-metastatic/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [Carboplatin](https://onco.cc/drugs/carboplatin/), [Paclitaxel / nab-paclitaxel](https://onco.cc/drugs/paclitaxel/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)

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