# A Phase II, EvaluateBLEX 404 Combined With Gemcitabine Monotherapy With Pancreatic Cancer

Source: https://onco.cc/trials/nct03301805/  
OnCo record `nct03301805` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in pancreatic cancer, run by Rgene Corporation, not yet recruiting.

## Summary

A Phase II, EvaluateBLEX 404 Combined With Gemcitabine Monotherapy With Pancreatic Cancer is a phase 2, interventional study registered as NCT03301805 by Rgene Corporation, with a registry enrolment figure of 40 participants, started 2026-07-01 and due to reach its primary completion in 2027-04-30. Interventions recorded: BLEX 404. Conditions listed: Pancreatic Cancer. Primary outcome: Part I: Dose-limiting toxicity (DLT) observation; Part II: Overall response rate (PR + CR). Pancreatic eligibility wording from the registry: "Patients with pathologically proved adenocarcinoma of pancreatic cancer and diagnosed with inoperable/metastatic disease (previous systemic chemotherapy, neoadjuvant or adjuvant gemcitabine are acceptable, unless exclusion criteria met)". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT03301805
- Phase: 2
- Setting: A Phase II, Open Label Study to Evaluate the Safety and Efficacy of BLEX 404 Oral Liquid Combined With Gemcitabine Monotherapy in Patients With Advanced Inoperable or Metastatic Pancreatic Cancer
- Sponsor: Rgene Corporation
- Enrolled: 40

## Sources

- ClinicalTrials.gov NCT03301805: https://clinicaltrials.gov/study/NCT03301805

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/), [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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