# A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

Source: https://onco.cc/trials/nct03505320/  
OnCo record `nct03505320` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Zolbetuximab, Oxaliplatin, Pembrolizumab, Leucovorin (folinic acid), Nivolumab and Docetaxel in gastric & gastro-oesophageal junction cancer, run by Astellas Pharma Global Development, Inc., active and no longer recruiting.

## Summary

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer is a phase 2 interventional study registered as NCT03505320 by Astellas Pharma Global Development, Inc., with 143 participants enrolled, started 2018-06-29 and due to reach its primary completion in 2027-06-30. Interventions recorded: zolbetuximab, oxaliplatin, leucovorin, fluorouracil, Pembrolizumab and folinic acid.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: pipeline; ctgov-ingest
- Registry id: NCT03505320
- Phase: 2
- Setting: A Phase 2 Study of Zolbetuximab (IMAB362) as Monotherapy and in Combination With Chemotherapy and/or Immunotherapy in Subjects With Metastatic or Locally Advanced Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma and Locoregional Gastric or GEJ Adenocarcinoma Whose Are Claudin (CLDN) 18.2 Positive
- Sponsor: Astellas Pharma Global Development, Inc.
- Enrolled: 143

## Sources

- ClinicalTrials.gov NCT03505320: https://clinicaltrials.gov/study/NCT03505320

## Connected records

- cancers: [Gastric & gastro-oesophageal junction cancer](https://onco.cc/cancers/gastric/)
- drugs: [Docetaxel](https://onco.cc/drugs/docetaxel/), [Leucovorin (folinic acid)](https://onco.cc/drugs/leucovorin/), [Nivolumab](https://onco.cc/drugs/nivolumab/), [Oxaliplatin](https://onco.cc/drugs/oxaliplatin/), [Pembrolizumab](https://onco.cc/drugs/pembrolizumab/), [Zolbetuximab](https://onco.cc/drugs/zolbetuximab/)
- companies: [Astellas](https://onco.cc/companies/astellas/)

---
JSON: https://onco.cc/api/v1/entities/nct03505320.json