# Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors

Source: https://onco.cc/trials/nct03755739/  
OnCo record `nct03755739` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2/3 trial in pancreatic cancer, run by Second Affiliated Hospital of Guangzhou Medical University, now recruiting.

## Summary

Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors is a phase 2/3, interventional study registered as NCT03755739 by Second Affiliated Hospital of Guangzhou Medical University, with a registry enrolment figure of 200 participants, started 2018-11-01 and due to reach its primary completion in 2033-11-01. Interventions recorded: Checkpoint inhibitor (CPI) such as Pembrolizumab plus chemotherapy. Conditions listed: Hepatocarcinoma; Lung Cancer; Melanoma; Renal Cancer; Head and Neck Cancer; Pancreas Cancer; Ovarian Cancer; Colo-rectal Cancer; Cervical Cancer; Breast Cancer. Primary outcome: Overall survival; Complete response (CR) rate before or at Month 6. Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT03755739
- Phase: 2/3
- Setting: A Phase II/III Trial of Comparison of Benefit of Administration of Checkpoint Inhibitors Plus Chemodrug Via Artery or Fine Needle to Tumor Versus Vein for Immunotherapy of Advanced Solid Tumors
- Sponsor: Second Affiliated Hospital of Guangzhou Medical University
- Enrolled: 200

## Sources

- ClinicalTrials.gov NCT03755739: https://clinicaltrials.gov/study/NCT03755739

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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