# QoL in mCRC Elderly Patients Receiving First-line Therapy Based on Simplified Geriatric Parameters.

Source: https://onco.cc/trials/nct03828227/  
OnCo record `nct03828227` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of capecitabine and bevacizumab (glioblastoma use) in colorectal cancer, run by GERCOR - Multidisciplinary Oncology Cooperative Group, active but no longer recruiting.

## Summary

QoL in mCRC Elderly Patients Receiving First-line Therapy Based on Simplified Geriatric Parameters. is a phase 3, randomised interventional study registered as NCT03828227 by GERCOR - Multidisciplinary Oncology Cooperative Group, with a registry enrolment figure of 49 participants, started 2019-06-14 and due to reach its primary completion in 2023-11-10. Interventions recorded: OPTIMOX-bevacizumab; Capecitabine plus bevacizumab. Conditions listed: Elderly Patients; Metastatic Colorectal Cancer; Quality of Life. Primary outcome: Health-related quality of life (HRQoL) at 6 months in the "candidate group".. Colorectal eligibility wording from the registry: "Histologically proven colorectal adenocarcinoma,". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-24
- Also known as: COLAGE
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT03828227
- Phase: 3
- Setting: Phase III Study to Evaluate the Quality of Life in Elderly Patients With Metastatic Colorectal Cancer Receiving First-line Therapy Based on Simplified Geriatric Parameters.
- Sponsor: GERCOR - Multidisciplinary Oncology Cooperative Group
- Enrolled: 49

## Sources

- ClinicalTrials.gov NCT03828227: https://clinicaltrials.gov/study/NCT03828227

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Bevacizumab (glioblastoma use)](https://onco.cc/drugs/bevacizumab-glioma/), [Capecitabine](https://onco.cc/drugs/capecitabine/)
- companies: [GERCOR](https://onco.cc/companies/gercor/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct03828227.json