# Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Source: https://onco.cc/trials/nct04044768/  
OnCo record `nct04044768` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Afamitresgene autoleucel in sarcomas, run by USWM CT, LLC, active and no longer recruiting.

## Summary

Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma is a phase 2 interventional study registered as NCT04044768 by USWM CT, LLC, with 52 participants enrolled, started 2019-08-13 and due to reach its primary completion in 2021-08-29. Interventions recorded: afamitresgene autoleucel (previously ADP-A2M4). Results have been posted on the registry.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: pipeline; ctgov-ingest
- Registry id: NCT04044768
- Phase: 2
- Setting: A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR™ T Cells in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
- Sponsor: USWM CT, LLC
- Enrolled: 52

## Sources

- ClinicalTrials.gov NCT04044768: https://clinicaltrials.gov/study/NCT04044768

## Connected records

- cancers: [Sarcomas (soft tissue, bone, GIST)](https://onco.cc/cancers/sarcoma/)
- drugs: [Afamitresgene autoleucel](https://onco.cc/drugs/afamitresgene-autoleucel/)

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