# A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Mul

Source: https://onco.cc/trials/nct04133636/  
OnCo record `nct04133636` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Ciltacabtagene autoleucel, Lenalidomide, Daratumumab in multiple myeloma, run by Janssen Research & Development, LLC, active and no longer recruiting.

## Summary

A Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against B-cell Maturation Antigen (BCMA) in Participants With Multiple Myeloma is a phase 2 interventional study registered as NCT04133636 by Janssen Research & Development, LLC, with 208 participants enrolled, started 2019-11-07 and due to reach its primary completion in 2027-02-26. Interventions recorded: JNJ-68284528, Lenalidomide, Daratumumab, Bortezomib, Dexamethasone. Conditions listed: Multiple Myeloma. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT04133636
- Phase: 2
- Setting: 68284528MMY2003: A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA in Subjects With Multiple Myeloma
- Sponsor: Janssen Research & Development, LLC
- Enrolled: 208

## Sources

- ClinicalTrials.gov NCT04133636: https://clinicaltrials.gov/study/NCT04133636

## Connected records

- cancers: [Multiple myeloma](https://onco.cc/cancers/multiple-myeloma/)
- drugs: [Bortezomib](https://onco.cc/drugs/bortezomib/), [Ciltacabtagene autoleucel](https://onco.cc/drugs/ciltacabtagene-autoleucel/), [Daratumumab](https://onco.cc/drugs/daratumumab/), [Dexamethasone](https://onco.cc/drugs/dexamethasone/), [Lenalidomide](https://onco.cc/drugs/lenalidomide/)
- companies: [Johnson & Johnson](https://onco.cc/companies/johnson-johnson/)

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