# Evaluation of 89Zr-DFO-nimotuzumab for Non-invasive Imaging of EGFR+ Cancers by Positron Emission Tomography (PET)

Source: https://onco.cc/trials/nct04235114/  
OnCo record `nct04235114` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial in colorectal cancer, run by University of Saskatchewan, now recruiting.

## Summary

Evaluation of 89Zr-DFO-nimotuzumab for Non-invasive Imaging of EGFR+ Cancers by Positron Emission Tomography (PET) is a phase 1/2, interventional study registered as NCT04235114 by University of Saskatchewan, with a registry enrolment figure of 14 participants, started 2020-02-01 and due to reach its primary completion in 2026-09. Interventions recorded: 50 mg 89Zr-DFO-Nimotuzumab; 1 mg 89Zr-DFO-Nimotuzumab. Conditions listed: Lung Cancer; Colorectal Cancer. Primary outcome: The observation of differences in 89Zr-DFO-nimotuzumab uptake between the tumors and normal tissues using PET/CT.. Colorectal eligibility wording from the registry: "* Not currently pregnant or nursing: If female subject must be surgically sterile (has had a documented bilateral oophorectomy and/or documented hysterectomy), post-menopausal (cessation of menses for \> 1 year), non-lactating, or of childbearing potential for whom a urine pregnancy test is negative". Sites: Canada. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT04235114
- Phase: 1/2
- Setting: Evaluation of 89Zr-DFO-nimotuzumab for Non-invasive Imaging of EGFR Positive Cancers by Positron Emission Tomography (PET)
- Sponsor: University of Saskatchewan
- Enrolled: 14

## Sources

- ClinicalTrials.gov NCT04235114: https://clinicaltrials.gov/study/NCT04235114

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct04235114.json