# A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokineti

Source: https://onco.cc/trials/nct04246086/  
OnCo record `nct04246086` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of Mosunetuzumab, Tocilizumab, Lenalidomide in follicular lymphoma, run by Hoffmann-La Roche, active and no longer recruiting.

## Summary

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma is a phase 1/2 interventional study registered as NCT04246086 by Hoffmann-La Roche, with 237 participants planned, started 2020-08-12 and due to reach its primary completion in 2030-09-06. Interventions recorded: Mosunetuzumab (IV), Tocilizumab, Lenalidomide, Mosunetuzumab (SC). Conditions listed: Follicular Lymphoma. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT04246086
- Phase: 1/2
- Setting: A Phase Ib/II, Open-Label, Multicenter Study With a Non-Randomized Stage Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab Plus Lenalidomide (+Len), and a Randomized Stage Evaluating the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Patients With Follicular Lymphoma
- Sponsor: Hoffmann-La Roche
- Enrolled: 237

## Sources

- ClinicalTrials.gov NCT04246086: https://clinicaltrials.gov/study/NCT04246086

## Connected records

- cancers: [Follicular lymphoma](https://onco.cc/cancers/follicular-lymphoma/)
- drugs: [Lenalidomide](https://onco.cc/drugs/lenalidomide/), [Mosunetuzumab](https://onco.cc/drugs/mosunetuzumab/), [Tocilizumab](https://onco.cc/drugs/tocilizumab/)
- companies: [Roche / Genentech](https://onco.cc/companies/roche-genentech/)

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