# Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

Source: https://onco.cc/trials/nct04317534/  
OnCo record `nct04317534` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of pembrolizumab in lung cancer, run by Greg Durm, MD, now recruiting.

## Summary

Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm is a phase 2, randomised interventional study registered as NCT04317534 by Greg Durm, MD, with a registry enrolment figure of 244 participants, started 2020-05-05 and due to reach its primary completion in 2027-04-08. Interventions recorded: Pembrolizumab. Conditions listed: NSCLC, Stage I. Primary outcome: Disease Free Survival (DFS). Lung eligibility wording from the registry: "* Patients must have undergone complete surgical resection of their stage I NSCLC between 4-12 weeks prior to registration and have negative surgical margins (R0)". Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT04317534
- Phase: 2
- Setting: A Randomized Phase II Trial of Adjuvant Pembrolizumab Versus Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm: Big Ten Cancer Research Consortium BTCRC-LUN18-153
- Sponsor: Greg Durm, MD
- Enrolled: 244

## Sources

- ClinicalTrials.gov NCT04317534: https://clinicaltrials.gov/study/NCT04317534

## Connected records

- cancers: [Resectable stage I to III non-small-cell lung cancer](https://onco.cc/cancers/resectable-nsclc/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/)
- drugs: [Pembrolizumab](https://onco.cc/drugs/pembrolizumab/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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