# Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer

Source: https://onco.cc/trials/nct04570943/  
OnCo record `nct04570943` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in pancreatic cancer, run by Institut du Cancer de Montpellier - Val d'Aurelle, now recruiting.

## Summary

Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer is a phase 2, interventional study registered as NCT04570943 by Institut du Cancer de Montpellier - Val d'Aurelle, with a registry enrolment figure of 103 participants, started 2021-06-16 and due to reach its primary completion in 2028-01. Interventions recorded: Gabrinox; MRI-GUIDED STEREOTACTIC RADIOTHERAPY. Conditions listed: Locally Advanced Pancreatic Adenocarcinoma. Primary outcome: Rate of non-progression at 4 months; Acute gastrointestinal non-toxicity rate. Pancreatic eligibility wording from the registry: "Histologically or cytologically proven pancreatic adenocarcinoma". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: GABRINOX-ART
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT04570943
- Phase: 2
- Setting: Phase II Study to Assess the Interest of a Sequential Treatment With Gemcitabine/Nab-paclitaxel (GEMBRAX) and Then FOLFIRINOX Followed by Stereotactic Magnetic Resonance-guided Adaptive Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
- Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle
- Enrolled: 103

## Sources

- ClinicalTrials.gov NCT04570943: https://clinicaltrials.gov/study/NCT04570943

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/)
- technologies: [SBRT / SABR (stereotactic radiotherapy)](https://onco.cc/technologies/sbrt/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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