# DNX-2440 for Resectable Colorectal Liver Metastasis

Source: https://onco.cc/trials/nct04714983/  
OnCo record `nct04714983` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1 trial of DNX-2440 run by DNAtrix, Inc., suspended.

## Summary

DNX-2440 for Resectable Colorectal Liver Metastasis is a phase 1 interventional study registered as NCT04714983 by DNAtrix, Inc., with 30 participants planned, started 2021-02-15. Conditions recorded: Liver Metastases, Liver Metastasis Colon Cancer, Colorectal Cancer, Breast Cancer, Gastric Cancer, Periampullary Cancer, Melanoma, Renal Cell Cancer, Sarcoma, Squamous Cell Carcinoma and Gastrointestinal Stromal Tumors. Interventions recorded: DNX-2440.

## Fields

- Kind: Trial
- Status: historic
- Last checked: 2026-11-03
- Tags: pipeline; ctgov-ingest
- Registry id: NCT04714983
- Phase: 1
- Setting: A Phase I Safety and Window-of-opportunity Study of Preoperative Intratumoral Injection of OX40-ligand Expressing Oncolytic Adenovirus (DNX-2440) in Patients With Resectable Liver Metastasis
- Sponsor: DNAtrix, Inc.
- Enrolled: 30

## Sources

- ClinicalTrials.gov NCT04714983: https://clinicaltrials.gov/study/NCT04714983

## Connected records

- cancers: [Ampullary cancer (ampulla of Vater)](https://onco.cc/cancers/ampullary/), [Breast cancer (all types)](https://onco.cc/cancers/breast-cancer/), [Colorectal cancer](https://onco.cc/cancers/colorectal/), [Gastric & gastro-oesophageal junction cancer](https://onco.cc/cancers/gastric/), [Gastrointestinal stromal tumour (GIST)](https://onco.cc/cancers/gist/), [Melanoma](https://onco.cc/cancers/melanoma/), [Metastatic cancer (cancer that has spread)](https://onco.cc/cancers/metastatic-cancer/), [Renal cell carcinoma](https://onco.cc/cancers/rcc/), [Sarcomas (soft tissue, bone, GIST)](https://onco.cc/cancers/sarcoma/)
- drugs: [DNX-2440](https://onco.cc/drugs/dnx-2440/)
- companies: [DNAtrix](https://onco.cc/companies/dnatrix/)

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JSON: https://onco.cc/api/v1/entities/nct04714983.json