# Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab in First Line Metastatic Non-squamous NSCLC

Source: https://onco.cc/trials/nct04786964/  
OnCo record `nct04786964` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Cosibelimab, Cisplatin, Carboplatin and Pemetrexed in Non-small-cell lung cancer, run by Checkpoint Therapeutics, Inc., recorded as terminated on the registry.

## Summary

Study of Pemetrexed+Platinum Chemotherapy With or Without Cosibelimab in First Line Metastatic Non-squamous NSCLC is a phase 3 interventional study registered as NCT04786964 by Checkpoint Therapeutics, Inc., with 25 participants recorded, started 2021-12-08 and due to reach its primary completion in 2023-12-30. Interventions recorded: Cosibelimab, Cisplatin, Carboplatin, Pemetrexed, Folic acid 350-1000 μg, Vitamin B12 1000 μg, Dexamethasone 4mg. Conditions recorded: Metastatic Non-squamous Non Small Cell Lung Cancer.

Linked to the drug Cosibelimab because the registry names it among its interventions and Non-small-cell lung cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT04786964
- Phase: 3
- Setting: A Randomized, Open-Label, Phase 3 Study of Cosibelimab (CK-301) in Combination With Platinum+Pemetrexed Chemotherapy in Subjects With First-Line Metastatic Non-squamous Non-Small Cell Lung Cancer
- Sponsor: Checkpoint Therapeutics, Inc.
- Enrolled: 25

## Sources

- ClinicalTrials.gov NCT04786964: https://clinicaltrials.gov/study/NCT04786964

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- drugs: [Carboplatin](https://onco.cc/drugs/carboplatin/), [Cisplatin](https://onco.cc/drugs/cisplatin/), [Cosibelimab](https://onco.cc/drugs/cosibelimab/), [Pemetrexed](https://onco.cc/drugs/pemetrexed/)
- companies: [Checkpoint Therapeutics](https://onco.cc/companies/checkpoint-therapeutics/)

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