# Aumolertinib with or Without Chemotherapy As 1st Line Treatment in Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Sensitizing EGFR Mut

Source: https://onco.cc/trials/nct04923906/  
OnCo record `nct04923906` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Aumolertinib in non-small-cell lung cancer and small-cell lung cancer, run by Jiangsu Hansoh Pharmaceutical Co., Ltd., active and no longer recruiting.

## Summary

Aumolertinib with or Without Chemotherapy As 1st Line Treatment in Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Sensitizing EGFR Mutations is a phase 3 interventional study registered as NCT04923906 by Jiangsu Hansoh Pharmaceutical Co., Ltd., with 624 participants planned, started 2021-08-11 and due to reach its primary completion in 2024-06-18. Interventions recorded: Aumolertinib, Placebo Aumolertinib. Conditions listed: Non-small Cell Lung Cancer. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT04923906
- Phase: 3
- Setting: Efficacy and Safety of Aumolertinib with or Without Chemotherapy As First-line Treatment in Locally Advanced or Metastatic Non-Small Cell Lung Cancer with Sensitizing Epidermal Growth Factor Receptor Mutations: a Randomized, Controlled, Open-label, Phase 3 and Multicenter Clinical Study
- Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd.
- Enrolled: 624

## Sources

- ClinicalTrials.gov NCT04923906: https://clinicaltrials.gov/study/NCT04923906

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- drugs: [Aumolertinib](https://onco.cc/drugs/aumolertinib/)

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