# Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage

Source: https://onco.cc/trials/nct05168839/  
OnCo record `nct05168839` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in colorectal cancer, run by Centre Hospitalier Universitaire de Besancon, now recruiting.

## Summary

Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage is a phase 3, randomised interventional study registered as NCT05168839 by Centre Hospitalier Universitaire de Besancon, with a registry enrolment figure of 1010 participants, started 2022-09-26 and due to reach its primary completion in 2025-10-31. Interventions recorded: FLUO+ : Intraoperative fluorescence angiography (IOFA) with indocyanine green (ICG).. Conditions listed: Colorectal Cancer. Primary outcome: Anastomotic leakage 90 days after surgery. Colorectal eligibility wording from the registry: "* Scheduled to undergo elective left colectomy or high rectal resection for cancer with intraperitoneal anastomosis". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: FLUOCOL-1
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT05168839
- Phase: 3
- Setting: Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage: a Single-blind Phase III Multicenter Randomized Controlled Trial (Intergroup FRENCH-GRECCAR Trial)
- Sponsor: Centre Hospitalier Universitaire de Besancon
- Enrolled: 1010

## Sources

- ClinicalTrials.gov NCT05168839: https://clinicaltrials.gov/study/NCT05168839

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [CAR-T cell therapy](https://onco.cc/technologies/car-t/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct05168839.json