# A Study Comparing Ensatinib Versus Platinum-Based Chemotherapy as Adjuvant Treatment for Stage II-IIIA ALK -Positive Non-Small Cell Lung Cancer

Source: https://onco.cc/trials/nct05186506/  
OnCo record `nct05186506` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in lung cancer, run by Sichuan University, not yet recruiting.

## Summary

A Study Comparing Ensatinib Versus Platinum-Based Chemotherapy as Adjuvant Treatment for Stage II-IIIA ALK -Positive Non-Small Cell Lung Cancer is a phase 2, randomised interventional study registered as NCT05186506 by Sichuan University, with a registry enrolment figure of 152 participants, started 2022-01-01 and due to reach its primary completion in 2025-12-15. Interventions recorded: Ensatinib; chemotherapy. Conditions listed: ALK Fusion Protein Expression; Adjuvant Therapy; Non-Small Cell Lung Cancer. Primary outcome: Disease free survival (DFS). Lung eligibility wording from the registry: "* Surgical resection of histologically confirmed Stage IIA to IIIA NSCLC with negative margins, ,within 10 weeks after the operation". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT05186506
- Phase: 2
- Setting: A Phase II, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of Ensatinib Versus Platinum-Based Chemotherapy as Adjuvant Treatment for Stage II-IIIA ALK -Positive Non-Small Cell Lung Cancer
- Sponsor: Sichuan University
- Enrolled: 152

## Sources

- ClinicalTrials.gov NCT05186506: https://clinicaltrials.gov/study/NCT05186506

## Connected records

- cancers: [ALK-positive non-small-cell lung cancer](https://onco.cc/cancers/alk-positive-nsclc/), [Resectable stage I to III non-small-cell lung cancer](https://onco.cc/cancers/resectable-nsclc/)
- companies: [Betta Pharmaceuticals](https://onco.cc/companies/betta/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct05186506.json