# A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Th

Source: https://onco.cc/trials/nct05201248/  
OnCo record `nct05201248` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of Epcoritamab, Cyclophosphamide, Rituximab in hodgkin lymphoma and non-hodgkin lymphoma, run by Genmab, active and no longer recruiting.

## Summary

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Therapies in Adult Participants in China With B-Cell Non-Hodgkin Lymphoma is a phase 1/2 interventional study registered as NCT05201248 by Genmab, with 49 participants enrolled, started 2022-03-10 and due to reach its primary completion in 2026-09. Interventions recorded: Epcoritamab, Cyclophosphamide, Rituximab, Doxorubicin, Vincristine. Conditions listed: B-Cell Non-Hodgkin Lymphoma. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT05201248
- Phase: 1/2
- Setting: Phase 1b/2, Open-Label Trial to Evaluate Safety and Preliminary Efficacy of Epcoritamab As Monotherapy or Combined With Standard-of-Care Therapies in Chinese Subjects With B-Cell Non-Hodgkin Lymphoma
- Sponsor: Genmab
- Enrolled: 49

## Sources

- ClinicalTrials.gov NCT05201248: https://clinicaltrials.gov/study/NCT05201248

## Connected records

- cancers: [Hodgkin lymphoma](https://onco.cc/cancers/hodgkin-lymphoma/), [Non-Hodgkin lymphoma (all types)](https://onco.cc/cancers/non-hodgkin-lymphoma/)
- drugs: [Cyclophosphamide](https://onco.cc/drugs/cyclophosphamide/), [Doxorubicin](https://onco.cc/drugs/doxorubicin/), [Epcoritamab](https://onco.cc/drugs/epcoritamab/), [Prednisone](https://onco.cc/drugs/prednisone/), [Rituximab](https://onco.cc/drugs/rituximab/), [Vincristine](https://onco.cc/drugs/vincristine/)
- companies: [Genmab](https://onco.cc/companies/genmab/)

---
JSON: https://onco.cc/api/v1/entities/nct05201248.json