# Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC

Source: https://onco.cc/trials/nct05278052/  
OnCo record `nct05278052` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in lung cancer, run by Tata Memorial Hospital, now recruiting.

## Summary

Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC is a phase 3, randomised interventional study registered as NCT05278052 by Tata Memorial Hospital, with a registry enrolment figure of 190 participants, started 2020-04-20 and due to reach its primary completion in 2026-04-20. Interventions recorded: Local consolidative radiation therapy; Standard maintenance therapy as decided by the treating medical oncologist. Conditions listed: Oligometastatic Disease; Metastatic Non Small Cell Lung Cancer. Primary outcome: Overall survival (OS). Lung eligibility wording from the registry: "Patients with pathologically proven diagnosis of NSCLC". Sites: India. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Also known as: TARGET-02
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT05278052
- Phase: 3
- Setting: Standard Maintenance Therapy Versus Local Consolidative Radiation Therapy and Standard Maintenance Therapy in 1-5 Sites of Oligometastatic Non-small Cell Lung Cancer (NSCLC): A Phase III Randomized Controlled Trial
- Sponsor: Tata Memorial Hospital
- Enrolled: 190

## Sources

- ClinicalTrials.gov NCT05278052: https://clinicaltrials.gov/study/NCT05278052

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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