# Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

Source: https://onco.cc/trials/nct05320198/  
OnCo record `nct05320198` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of DISC-0974 in myeloproliferative neoplasms and myelodysplastic syndromes / neoplasms, run by Disc Medicine, Inc, now recruiting.

## Summary

Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia is a phase 1/2 interventional study registered as NCT05320198 by Disc Medicine, Inc, with 150 participants planned, started 2022-06-06 and due to reach its primary completion in 2027-05. Interventions recorded: DISC-0974.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-16
- Tags: pipeline; ctgov-ingest
- Registry id: NCT05320198
- Phase: 1/2
- Setting: RALLY-MF: A Phase 1b/2 Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of DISC-0974 in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia
- Sponsor: Disc Medicine, Inc
- Enrolled: 150

## Sources

- ClinicalTrials.gov NCT05320198: https://clinicaltrials.gov/study/NCT05320198

## Connected records

- cancers: [Myelodysplastic syndromes / neoplasms (MDS)](https://onco.cc/cancers/mds/), [Myeloproliferative neoplasms (PV, ET, myelofibrosis)](https://onco.cc/cancers/myeloproliferative-neoplasms/)

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