# NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer)

Source: https://onco.cc/trials/nct05529940/  
OnCo record `nct05529940` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of fOLFIRINOX / mFOLFIRINOX in pancreatic cancer, run by Seoul National University Hospital, now recruiting.

## Summary

NeoFOL-R Trial (Perioperative Versus Adjuvnat FOLFIRINOX in Resectable Pancreatic Cancer) is a phase 3, randomised interventional study registered as NCT05529940 by Seoul National University Hospital, with a registry enrolment figure of 609 participants, started 2023-04-01 and due to reach its primary completion in 2024-12. Interventions recorded: Folfirinox. Conditions listed: Resectable Pancreatic Cancer; Neoadjuvant Chemotherapy; Effects of Chemotherapy. Primary outcome: 2-year survival rate. Pancreatic eligibility wording from the registry: "Pancreatic ductal adenocarcinoma diagnosed by histological examination (histologic or cytopathological) D". Sites: South Korea. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT05529940
- Phase: 3
- Setting: Efficacy of Perioperative Versus Adjuvant FOLFIRINOX in Resectable Pancreatic Cancer: an International Multicenter Randomized Controlled Trial (NeoFOL-R Trial)
- Sponsor: Seoul National University Hospital
- Enrolled: 609

## Sources

- ClinicalTrials.gov NCT05529940: https://clinicaltrials.gov/study/NCT05529940

## Connected records

- cancers: [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/), [Topoisomerase-I inhibitors (and ADC payloads)](https://onco.cc/technologies/topoisomerase-inhibitors/)
- drugs: [FOLFIRINOX / mFOLFIRINOX](https://onco.cc/drugs/folfirinox/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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