# Study of SGR-1505 in Mature B-Cell Neoplasms

Source: https://onco.cc/trials/nct05544019/  
OnCo record `nct05544019` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1 trial of SGR-1505 run by Schrödinger, Inc., now recruiting.

## Summary

Study of SGR-1505 in Mature B-Cell Neoplasms is a phase 1 interventional study registered as NCT05544019 by Schrödinger, Inc., with 98 participants planned, started 2023-04-10. Conditions recorded: Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL, Waldenstrom Macroglobulinemia, MALT Lymphoma, Follicular Lymphoma, Pediatric-Type Follicular Lymphoma, IRF4 Gene Rearrangement, EBV-Positive DLBCL, Nos, Burkitt Lymphoma, Plasmablastic Lymphoma, High-grade B-cell Lymphoma, Primary Cutaneous Follicle Center Lymphoma, Primary Effusion Lymphoma, Mantle Cell Lymphoma, DLBCL Germinal Center B-Cell Type, Primary Mediastinal Large B Cell Lymphoma, T-Cell/Histiocyte Rich Lymphoma, ALK-Positive Large B-Cell Lymphoma, Primary Cutaneous Diffuse Large B-Cell Lymphoma, Splenic Marginal Zone Lymphoma, Chronic Lymphocytic Leukemia, Nodal Marginal Zone Lymphoma, HHV8-Positive DLBCL, Nos, Lymphoplasmacytic Lymphoma and Duodenal-Type Follicular Lymphoma. Interventions recorded: SGR-1505.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-11-03
- Tags: pipeline; ctgov-ingest
- Registry id: NCT05544019
- Phase: 1
- Setting: A Phase 1, Open-Label, Multicenter, Dose Escalation Study of SGR-1505 as Monotherapy in Subjects With Mature B-Cell Malignancies
- Sponsor: Schrödinger, Inc.
- Enrolled: 98

## Sources

- ClinicalTrials.gov NCT05544019: https://clinicaltrials.gov/study/NCT05544019

## Connected records

- cancers: [Burkitt lymphoma](https://onco.cc/cancers/burkitt-lymphoma/), [Chronic lymphocytic leukaemia](https://onco.cc/cancers/cll/), [Diffuse large B-cell lymphoma](https://onco.cc/cancers/dlbcl/), [Follicular lymphoma](https://onco.cc/cancers/follicular-lymphoma/), [Mantle cell lymphoma](https://onco.cc/cancers/mantle-cell-lymphoma/), [Marginal zone lymphoma](https://onco.cc/cancers/marginal-zone-lymphoma/), [Non-Hodgkin lymphoma (all types)](https://onco.cc/cancers/non-hodgkin-lymphoma/), [Plasmablastic lymphoma](https://onco.cc/cancers/plasmablastic-lymphoma/), [Primary cutaneous follicle centre lymphoma](https://onco.cc/cancers/primary-cutaneous-follicle-centre-lymphoma/), [Primary effusion lymphoma](https://onco.cc/cancers/primary-effusion-lymphoma/), [Primary mediastinal (thymic) large B-cell lymphoma](https://onco.cc/cancers/primary-mediastinal-b-cell-lymphoma/), [Waldenström macroglobulinaemia](https://onco.cc/cancers/waldenstrom/)
- drugs: [SGR-1505](https://onco.cc/drugs/sgr-1505/)
- companies: [Schrödinger](https://onco.cc/companies/schrodinger/)

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