# Study of Novel Treatment Combinations in Patients With Lung Cancer

Source: https://onco.cc/trials/nct05633667/  
OnCo record `nct05633667` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Zimberelimab, Domvanalimab, Sacituzumab govitecan in non-small-cell lung cancer and small-cell lung cancer, run by Gilead Sciences, active and no longer recruiting.

## Summary

Study of Novel Treatment Combinations in Patients With Lung Cancer is a phase 2 interventional study registered as NCT05633667 by Gilead Sciences, with 192 participants enrolled, started 2023-03-16 and due to reach its primary completion in 2029-09. Interventions recorded: Zimberelimab (ZIM), Domvanalimab (DOM), Sacituzumab govitecan-hziy (SG), Etrumadenant (ETRUMA), Carboplatin. Conditions listed: Lung Cancer, Advanced or Metastatic Non-Small-Cell Lung Cancer, Resectable Non-Small-Cell Lung Cancer. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT05633667
- Phase: 2
- Setting: A Phase 2 Platform Study Evaluating the Safety and Efficacy of Novel Treatment Combinations in Patients With Lung Cancer (VELOCITY-Lung)
- Sponsor: Gilead Sciences
- Enrolled: 192

## Sources

- ClinicalTrials.gov NCT05633667: https://clinicaltrials.gov/study/NCT05633667

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- drugs: [Carboplatin](https://onco.cc/drugs/carboplatin/), [Cisplatin](https://onco.cc/drugs/cisplatin/), [Domvanalimab](https://onco.cc/drugs/domvanalimab/), [Pemetrexed](https://onco.cc/drugs/pemetrexed/), [Sacituzumab govitecan](https://onco.cc/drugs/sacituzumab-govitecan/), [Zimberelimab](https://onco.cc/drugs/zimberelimab/)
- companies: [Gilead Sciences (incl. Kite)](https://onco.cc/companies/gilead/)

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JSON: https://onco.cc/api/v1/entities/nct05633667.json