# CAPEOX vs Observation in Colorectal Cancer Patients With Positive MRD

Source: https://onco.cc/trials/nct05699746/  
OnCo record `nct05699746` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of capecitabine and fOLFOX (5-FU, leucovorin, oxaliplatin) in colorectal cancer, run by Zhejiang University, not yet recruiting.

## Summary

CAPEOX vs Observation in Colorectal Cancer Patients With Positive MRD is a phase 3, randomised interventional study registered as NCT05699746 by Zhejiang University, with a registry enrolment figure of 38 participants, started 2023-03 and due to reach its primary completion in 2026-09. Interventions recorded: Capecitabine tablets; Oxaliplatin. Conditions listed: Colorectal Cancer. Primary outcome: Recurrence-free survival. Colorectal eligibility wording from the registry: "Colorectal cancer confirmed by pathology, and the TNM stage (AJCC v8) is stage I or stage II". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT05699746
- Phase: 3
- Setting: A Randomized Controlled Trial of CAPEOX vs Observation in Early-stage Colorectal Cancer Patients With Positive MRD After Curative Surgery
- Sponsor: Zhejiang University
- Enrolled: 38

## Sources

- ClinicalTrials.gov NCT05699746: https://clinicaltrials.gov/study/NCT05699746

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [Capecitabine](https://onco.cc/drugs/capecitabine/), [FOLFOX (5-FU, leucovorin, oxaliplatin)](https://onco.cc/drugs/folfox/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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