# Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases

Source: https://onco.cc/trials/nct05742425/  
OnCo record `nct05742425` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Second Affiliated Hospital, Zhejiang University, School of Medicine, now recruiting.

## Summary

Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases is a phase 2, interventional study registered as NCT05742425 by Second Affiliated Hospital, Zhejiang University, School of Medicine, with a registry enrolment figure of 30 participants, started 2023-03 and due to reach its primary completion in 2028-03. Interventions recorded: Serplulimab Combined With FOLFIRI and Bevacizumab. Conditions listed: Unresectable Colon Cancer Peritoneal Metastases; PMMR/Ras/BRAF Wild-type. Primary outcome: Disease-free survival (DFS). Colorectal eligibility wording from the registry: "Colon cancer was confirmed by histology, and its gene detection was pMMR/MSS and RAS/BRAF wild-type". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT05742425
- Phase: 2
- Setting: The Efficacy and Safety of Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of pMMR/Ras/BRAF Wild-type Unresectable Colon Cancer Peritoneal Metastases: a Multicenter Single-arm Phase II Trial
- Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine
- Enrolled: 30

## Sources

- ClinicalTrials.gov NCT05742425: https://clinicaltrials.gov/study/NCT05742425

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct05742425.json