# Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients

Source: https://onco.cc/trials/nct05797467/  
OnCo record `nct05797467` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of bevacizumab (glioblastoma use) in colorectal cancer, run by Sixth Affiliated Hospital, Sun Yat-sen University, now recruiting.

## Summary

Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients is a phase 3, randomised interventional study registered as NCT05797467 by Sixth Affiliated Hospital, Sun Yat-sen University, with a registry enrolment figure of 366 participants, started 2023-04-01 and due to reach its primary completion in 2030-04-01. Interventions recorded: FOLFOX chemotherapy regimens; Bevacizumab. Conditions listed: Colorectal Cancer; Chemotherapy Effect. Primary outcome: 3-year disease-free survival; 5-year disease-free survival; median of disease-free survival. Colorectal eligibility wording from the registry: "Pathologically confirmed pT3-4N2 stage colorectal adenocarcinoma after surgery;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT05797467
- Phase: 3
- Setting: Adjuvant Chemotherapy Combined With Targeted Therapy Versus Adjuvant Chemotherapy Alone in the Treatment of Stage T3-4N2 Colorectal Cancer:A Multicenter, Randomized, Phase III Clinical Trail
- Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University
- Enrolled: 366

## Sources

- ClinicalTrials.gov NCT05797467: https://clinicaltrials.gov/study/NCT05797467

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- drugs: [Bevacizumab (glioblastoma use)](https://onco.cc/drugs/bevacizumab-glioma/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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