# Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer

Source: https://onco.cc/trials/nct05806931/  
OnCo record `nct05806931` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of bevacizumab (glioblastoma use) in colorectal cancer, run by Rutgers, The State University of New Jersey, now recruiting.

## Summary

Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer is a phase 2, interventional study registered as NCT05806931 by Rutgers, The State University of New Jersey, with a registry enrolment figure of 50 participants, started 2023-05-17 and due to reach its primary completion in 2026-05-01. Interventions recorded: TAS-102, oxaliplatin, irinotecan with bevacizumab. Conditions listed: Colon Cancer; Rectal Cancer. Primary outcome: Disease control rate (DCR):. Colorectal eligibility wording from the registry: "* Histologically confirmed stage IV colon cancer (AJCC 7th edition) that has progressed after standard therapy that included 5-FU, irinotecan, oxaliplatin and appropriate antibody therapy". Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: SCOTI
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT05806931
- Phase: 2
- Setting: Sequential Combined TAS-102 and Oxaliplatin Alternating With TAS-102 and Irinotecan (Sequential TASOXIRI) With Bevacizumab for Late-Line Metastatic Colorectal Cancer
- Sponsor: Rutgers, The State University of New Jersey
- Enrolled: 50

## Sources

- ClinicalTrials.gov NCT05806931: https://clinicaltrials.gov/study/NCT05806931

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- drugs: [Bevacizumab (glioblastoma use)](https://onco.cc/drugs/bevacizumab-glioma/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct05806931.json