# Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer

Source: https://onco.cc/trials/nct05810792/  
OnCo record `nct05810792` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of histamine dihydrochloride and aldesleukin (high-dose IL-2) in pancreatic cancer, run by Sahlgrenska University Hospital, not yet recruiting.

## Summary

Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer is a phase 2, interventional study registered as NCT05810792 by Sahlgrenska University Hospital, with a registry enrolment figure of 50 participants, started 2024-04-01 and due to reach its primary completion in 2027-04-01. Interventions recorded: Histamine Dihydrochloride (HDC); Interleukin-2 (IL-2). Conditions listed: Pancreatic Cancer; Surgery; Metastasis; Immunosuppression. Primary outcome: Incidence and severity of Treatment-Emergent Adverse Events as assessed by NCI-CTCAE. Pancreatic eligibility wording from the registry: "By the surgeon´s evaluation fit for pancreatic surgery". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: PANCEP-1
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT05810792
- Phase: 2
- Setting: A Phase I/II Trial of Peri- and Postoperative Treatment With Histamine Dihydrochloride and Low-dose Interleukin-2 in Patients With Primary Resectable Pancreatic Cancer
- Sponsor: Sahlgrenska University Hospital
- Enrolled: 50

## Sources

- ClinicalTrials.gov NCT05810792: https://clinicaltrials.gov/study/NCT05810792

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/), [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- drugs: [Aldesleukin (high-dose IL-2)](https://onco.cc/drugs/aldesleukin/), [Histamine dihydrochloride](https://onco.cc/drugs/histamine-dihydrochloride/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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