# Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients with Non-resectable Pancreatic Cancer

Source: https://onco.cc/trials/nct05841420/  
OnCo record `nct05841420` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of gemcitabine and nab-paclitaxel in pancreatic cancer, run by Morten Ladekarl, now recruiting.

## Summary

Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients with Non-resectable Pancreatic Cancer is a phase 2, randomised interventional study registered as NCT05841420 by Morten Ladekarl, with a registry enrolment figure of 98 participants, started 2023-06-12 and due to reach its primary completion in 2025-06. Interventions recorded: Gemcitabine; Nab paclitaxel. Conditions listed: Pancreas Cancer; Non-Resectable Pancreas Carcinoma. Primary outcome: PFS (Progression Free Survival). Pancreatic eligibility wording from the registry: "* Adenocarcinoma of the pancreas, histopathologically or cytologically verified". Sites: Denmark. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT05841420
- Phase: 2
- Setting: A Randomized Phase II Study of Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients with Non-resectable Pancreatic Cancer
- Sponsor: Morten Ladekarl
- Enrolled: 98

## Sources

- ClinicalTrials.gov NCT05841420: https://clinicaltrials.gov/study/NCT05841420

## Connected records

- cancers: [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Gemcitabine](https://onco.cc/drugs/gemcitabine/), [Nab-paclitaxel](https://onco.cc/drugs/nab-paclitaxel/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct05841420.json