# COLLISION RELAPSE Trial

Source: https://onco.cc/trials/nct05861505/  
OnCo record `nct05861505` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial in colorectal cancer, run by Amsterdam UMC, location VUmc, now recruiting.

## Summary

COLLISION RELAPSE Trial is a phase 3, randomised interventional study registered as NCT05861505 by Amsterdam UMC, location VUmc, with a registry enrolment figure of 360 participants, started 2023-04-24 and due to reach its primary completion in 2027-05-01. Interventions recorded: Neoadjuvant systemic therapy (CAPOX+/-B FOLFOX+/-B FOLFIRI+/-B); Repeat local treatment. Conditions listed: Colorectal Cancer; Liver Metastases; Liver Metastasis Colon Cancer; Chemotherapy Effect; Surgery; Recurrence. Primary outcome: Overall survival (OS) per patient. Colorectal eligibility wording from the registry: "* Histological documentation of primary colorectal tumor". Sites: Netherlands. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT05861505
- Phase: 3
- Setting: COLLISION RELAPSE Trial - Recurrent Colorectal Liver Metastases: Repeat Local Treatment +/- Neoadjuvant Systemic Therapy - a Phase III Prospective Randomized Controlled Trial
- Sponsor: Amsterdam UMC, location VUmc
- Enrolled: 360

## Sources

- ClinicalTrials.gov NCT05861505: https://clinicaltrials.gov/study/NCT05861505

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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JSON: https://onco.cc/api/v1/entities/nct05861505.json