# A Phase II/III Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer

Source: https://onco.cc/trials/nct05945901/  
OnCo record `nct05945901` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2/3 trial testing HR070803 in colorectal cancer, active and no longer recruiting.

## Summary

A Phase II/III Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer is a phase 2/3 interventional study registered as NCT05945901, led by Jiangsu HengRui Medicine, and active but no longer recruiting on the registry. Official title: A Phase II/III, Double-blind, Randomised, Multi-centre Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer. Planned enrolment is 669 participants (actual). The study started in 2023-08-14 and primary completion is expected in 2025-12-01. No results have been posted on ClinicalTrials.gov.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-11
- Tags: ctgov-ingest
- Registry id: NCT05945901
- Phase: 2/3
- Setting: A Phase II/III, Double-blind, Randomized, Multi-center Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer
- Sponsor: Jiangsu HengRui Medicine
- Enrolled: 669

## Sources

- ClinicalTrials.gov NCT05945901: https://clinicaltrials.gov/study/NCT05945901

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/)
- drugs: [HR070803](https://onco.cc/drugs/hr070803/)
- companies: [Jiangsu Hengrui Pharmaceuticals](https://onco.cc/companies/hengrui/)

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