# NIR-Fluorescence Guided Surgical Resection of Neoadjuvant Treated Localized Pancreatic Cancer Using SGM-101

Source: https://onco.cc/trials/nct05984810/  
OnCo record `nct05984810` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in pancreatic cancer, run by Leiden University Medical Center, now recruiting.

## Summary

NIR-Fluorescence Guided Surgical Resection of Neoadjuvant Treated Localized Pancreatic Cancer Using SGM-101 is a phase 2, interventional study registered as NCT05984810 by Leiden University Medical Center, with a registry enrolment figure of 20 participants, started 2024-03-18 and due to reach its primary completion in 2026-12. Interventions recorded: Fluorescence-guided surgery using CEA-targeted fluorophore SGM-101. Conditions listed: Pancreas Adenocarcinoma. Primary outcome: Intra-operative visualization of neoadjuvant treated pancreatic tumors using Near-infrared fluorescence imaging,. Pancreatic eligibility wording from the registry: "Neoadjuvant treated (borderline) resectable or locally advanced pancreatic cancer scheduled for a surgical resection". Sites: Netherlands. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: FLUOPANC-II
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT05984810
- Phase: 2
- Setting: A Performance Study of SGM-101, a Fluorochrome-labeled Anti-carcinoembryonic Antigen Monoclonal Antibody for Fluorescence-guided Imaging to Determine Local Extent and Resectability During Surgical Resection of Pancreatic Ductal Adenocarcinoma After Neoadjuvant Treatment
- Sponsor: Leiden University Medical Center
- Enrolled: 20

## Sources

- ClinicalTrials.gov NCT05984810: https://clinicaltrials.gov/study/NCT05984810

## Connected records

- cancers: [Borderline resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/borderline-resectable-pdac/), [Locally advanced unresectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/locally-advanced-pdac/), [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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