# Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)

Source: https://onco.cc/trials/nct06066424/  
OnCo record `nct06066424` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

An early trial studying the safety and activity of experimental treatment. Its registry status does not establish patient benefit.

## Summary

Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA). ClinicalTrials.gov record last updated 2026-10-06: recruiting. Enrollment is planned at 54 participants. Primary completion is estimated at 2038-04-30. No tabular results are posted on ClinicalTrials.gov; this does not exclude separate publications.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-10-06
- Registry id: NCT06066424
- Phase: 1
- Setting: Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)
- Sponsor: M.D. Anderson Cancer Center

## Notes

- ClinicalTrials.gov record last updated 2026-10-06: recruiting. Enrollment is planned at 54 participants. Primary completion is estimated at 2038-04-30. No tabular results are posted on ClinicalTrials.gov; this does not exclude separate publications.

## Sources

- ClinicalTrials.gov NCT06066424: https://clinicaltrials.gov/study/NCT06066424

## Connected records

- targets: [TROP2](https://onco.cc/targets/trop2/)
- drugs: [TROP2 CAR/IL-15 cord-blood NK cells](https://onco.cc/drugs/trop2-car-il15-cord-blood-nk/)

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JSON: https://onco.cc/api/v1/entities/nct06066424.json