# PACCELIO - FDG-PET Based Small Volume Accelerated Immuno Chemoradiotherapy in Locally Advanced NSCLC

Source: https://onco.cc/trials/nct06102057/  
OnCo record `nct06102057` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in lung cancer, run by TheraOp, now recruiting.

## Summary

PACCELIO - FDG-PET Based Small Volume Accelerated Immuno Chemoradiotherapy in Locally Advanced NSCLC is a phase 2, randomised interventional study registered as NCT06102057 by TheraOp, with a registry enrolment figure of 110 participants, started 2024-07-01 and due to reach its primary completion in 2026-06. Interventions recorded: standard Radiotherapy; Chemotherapy; Immunotherapy; Experimental Radiotherapy. Conditions listed: Stage III Non-small Cell Lung Cancer; Locally Advanced; Unresectable. Primary outcome: Comparison of the Completion rate of Experimental Arm to Conventional Arm. Lung eligibility wording from the registry: "* Patients with histologically or cytologically documented NSCLC who present with locally advanced, unresectable (Stage III) disease (according to version 8 of the International Association for the Study of Lung Cancer Staging Manual in Thoracic Oncology (IASLC Staging Manual in Thoracic Oncology 20". Sites: Germany, Switzerland. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-25
- Also known as: PACCELIO
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT06102057
- Phase: 2
- Setting: PACCELIO - FDG-PET Based Small Volume Accelerated Immuno Chemoradiotherapy in Locally Advanced NSCLC
- Sponsor: TheraOp
- Enrolled: 110

## Sources

- ClinicalTrials.gov NCT06102057: https://clinicaltrials.gov/study/NCT06102057

## Connected records

- cancers: [Unresectable stage III non-small-cell lung cancer](https://onco.cc/cancers/stage-iii-unresectable-nsclc/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- companies: [AstraZeneca](https://onco.cc/companies/astrazeneca/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

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