# Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC.

Source: https://onco.cc/trials/nct06145074/  
OnCo record `nct06145074` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of propranolol (Hemangeol) in pancreatic cancer, run by Zealand University Hospital, now recruiting.

## Summary

Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC. is a phase 2, randomised interventional study registered as NCT06145074 by Zealand University Hospital, with a registry enrolment figure of 30 participants, started 2024-03-20 and due to reach its primary completion in 2026-12-31. Interventions recorded: Propranolol; Placebo. Conditions listed: Pancreatic Cancer; Surgery. Primary outcome: Preoperative anxiety; Preoperative anxiety and depression; Preoperative quality of life. Pancreatic eligibility wording from the registry: "* Patients with suspected surgically resectable pancreatic cancer". Sites: Denmark. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: IMPULS
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT06145074
- Phase: 2
- Setting: Examining the Impact of Propranolol on Preoperative Anxiety and on Tumorigenic Changes in Patients With Pancreatic Ductal Adenocarcinomas: a Randomized, Triple-blinded, Placebo-controlled Pilot Trial
- Sponsor: Zealand University Hospital
- Enrolled: 30

## Sources

- ClinicalTrials.gov NCT06145074: https://clinicaltrials.gov/study/NCT06145074

## Connected records

- cancers: [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- drugs: [Propranolol (Hemangeol)](https://onco.cc/drugs/propranolol-hemangeol/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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