# A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemoth

Source: https://onco.cc/trials/nct06161441/  
OnCo record `nct06161441` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Fianlimab, Cemiplimab, Pemetrexed in non-small-cell lung cancer and small-cell lung cancer, run by Regeneron Pharmaceuticals, active and no longer recruiting.

## Summary

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery is a phase 2 interventional study registered as NCT06161441 by Regeneron Pharmaceuticals, with 195 participants enrolled, started 2024-07-16 and due to reach its primary completion in 2026-08-24. Interventions recorded: Fianlimab, Cemiplimab, Pemetrexed, Paclitaxel, Carboplatin. Conditions listed: Resectable Non-small Cell Lung Cancer. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-16
- Tags: ctgov-ingest
- Registry id: NCT06161441
- Phase: 2
- Setting: A Phase 2 Peri-Operative Trial of Fianlimab and Cemiplimab in Combination With Chemotherapy Versus Cemiplimab in Combination With Chemotherapy in Patients With Resectable Early Stage (Stage II to IIIB [N2]) NSCLC
- Sponsor: Regeneron Pharmaceuticals
- Enrolled: 195

## Sources

- ClinicalTrials.gov NCT06161441: https://clinicaltrials.gov/study/NCT06161441

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/), [Small-cell lung cancer](https://onco.cc/cancers/sclc/)
- drugs: [Carboplatin](https://onco.cc/drugs/carboplatin/), [Cemiplimab](https://onco.cc/drugs/cemiplimab/), [Cisplatin](https://onco.cc/drugs/cisplatin/), [Fianlimab](https://onco.cc/drugs/fianlimab/), [Paclitaxel / nab-paclitaxel](https://onco.cc/drugs/paclitaxel/), [Pemetrexed](https://onco.cc/drugs/pemetrexed/)
- companies: [Regeneron](https://onco.cc/companies/regeneron/)

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JSON: https://onco.cc/api/v1/entities/nct06161441.json