# Perioperative Treatment in High-risk Resectable Pancreatic Cancer With NALIRIFOX

Source: https://onco.cc/trials/nct06210360/  
OnCo record `nct06210360` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of liposomal irinotecan, cAPOX (capecitabine, oxaliplatin), fluorouracil (5-FU) and leucovorin (folinic acid) in pancreatic cancer, run by Changhai Hospital, not yet recruiting.

## Summary

Perioperative Treatment in High-risk Resectable Pancreatic Cancer With NALIRIFOX is a phase 2, randomised interventional study registered as NCT06210360 by Changhai Hospital, with a registry enrolment figure of 134 participants, started 2024-02-01 and due to reach its primary completion in 2025-04-01. Interventions recorded: Irinotecan liposome injection; Oxaliplatin; 5-FU; LV. Conditions listed: Pancreatic Cancer. Primary outcome: 2-year Overall Survival Rate. Pancreatic eligibility wording from the registry: "Histologically or cytologically proven pancreatic ductal adenocarcinoma". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Tags: ctgov-ingest; pancreatic-deep-dive
- Registry id: NCT06210360
- Phase: 2
- Setting: NALIRIFOX as Perioperative Treatment in Patients With High-risk Resectable Pancreatic Cancer : a Multicenter, Randomized, Open-label Trial
- Sponsor: Changhai Hospital
- Enrolled: 134

## Sources

- ClinicalTrials.gov NCT06210360: https://clinicaltrials.gov/study/NCT06210360

## Connected records

- cancers: [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Topoisomerase-I inhibitors (and ADC payloads)](https://onco.cc/technologies/topoisomerase-inhibitors/)
- drugs: [CAPOX (capecitabine, oxaliplatin)](https://onco.cc/drugs/capox/), [Fluorouracil (5-FU)](https://onco.cc/drugs/fluorouracil/), [Leucovorin (folinic acid)](https://onco.cc/drugs/leucovorin/), [Liposomal irinotecan](https://onco.cc/drugs/liposomal-irinotecan/)
- terms: [Pancreatic cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/pancreatic-trials-open-today/)

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