# Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma

Source: https://onco.cc/trials/nct06220032/  
OnCo record `nct06220032` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Dexrazoxane, Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, Lenalidomide and Pegfilgrastim in Diffuse large B-cell lymphoma, run by Stichting Hemato-Oncologie voor Volwassenen Nederland, now recruiting.

## Summary

Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma is a phase 3 interventional study registered as NCT06220032 by Stichting Hemato-Oncologie voor Volwassenen Nederland, with 324 participants planned, started 2024-08-15 and due to reach its primary completion in 2028-12-15. Interventions recorded: Dexrazoxane, Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone, Lenalidomide, Pegfilgrastim. Conditions recorded: DLBCL - Diffuse Large B Cell Lymphoma.

Linked to the drug Dexrazoxane because the registry names it among its interventions and Diffuse large B-cell lymphoma among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT06220032
- Phase: 3
- Setting: ANTICIPATE: Prevention of ANThracycline-Induced Cardiac Dysfunction by Dexrazoxane In PATients With diffusE Large B-cell Lymphoma: a Phase III National Multicenter Prospective Randomized Open-label Trial
- Sponsor: Stichting Hemato-Oncologie voor Volwassenen Nederland
- Enrolled: 324

## Sources

- ClinicalTrials.gov NCT06220032: https://clinicaltrials.gov/study/NCT06220032

## Connected records

- cancers: [Diffuse large B-cell lymphoma](https://onco.cc/cancers/dlbcl/)
- drugs: [Cyclophosphamide](https://onco.cc/drugs/cyclophosphamide/), [Dexrazoxane](https://onco.cc/drugs/dexrazoxane/), [Doxorubicin](https://onco.cc/drugs/doxorubicin/), [Lenalidomide](https://onco.cc/drugs/lenalidomide/), [Pegfilgrastim](https://onco.cc/drugs/pegfilgrastim/), [Prednisone](https://onco.cc/drugs/prednisone/), [Rituximab](https://onco.cc/drugs/rituximab/), [Vincristine](https://onco.cc/drugs/vincristine/)

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JSON: https://onco.cc/api/v1/entities/nct06220032.json