# Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer

Source: https://onco.cc/trials/nct06226857/  
OnCo record `nct06226857` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of cetuximab in colorectal cancer, run by City Clinical Oncology Hospital No 1, now recruiting.

## Summary

Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer is a phase 3, randomised interventional study registered as NCT06226857 by City Clinical Oncology Hospital No 1, with a registry enrolment figure of 355 participants, started 2024-01-17 and due to reach its primary completion in 2026-12-31. Interventions recorded: Cetuximab. Conditions listed: Colorectal Neoplasms; Chemotherapy Effect; Molecular Sequence Variation. Primary outcome: progression-free survival. Colorectal eligibility wording from the registry: "Verified diagnosis of colorectal adenocarcinoma (C18". Sites: Russia. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: CRC01
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06226857
- Phase: 3
- Setting: Predictive Value of Other Oncogene Mutations for Anti-EGFR Monoclonal Antibodies Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer: Multicenter Randomized Phase III Trial
- Sponsor: City Clinical Oncology Hospital No 1
- Enrolled: 355

## Sources

- ClinicalTrials.gov NCT06226857: https://clinicaltrials.gov/study/NCT06226857

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Monoclonal antibodies](https://onco.cc/technologies/monoclonal-antibody/)
- drugs: [Cetuximab](https://onco.cc/drugs/cetuximab/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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