# Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Mult

Source: https://onco.cc/trials/nct06234007/  
OnCo record `nct06234007` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial in colorectal cancer, run by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, now recruiting.

## Summary

Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study is a phase 2, interventional study registered as NCT06234007 by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, with a registry enrolment figure of 45 participants, started 2023-12-01 and due to reach its primary completion in 2024-12-31. Interventions recorded: Fruquintinib, Adebrelimab, Oxaliplatin, Capecitabine. Conditions listed: Locally Advanced Rectal Cancer. Primary outcome: pathology complete response(pCR). Colorectal eligibility wording from the registry: "Locally advanced rectal adenocarcinoma confirmed by histopathology;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06234007
- Phase: 2
- Setting: Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study (UNION PRECISION-I)
- Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
- Enrolled: 45

## Sources

- ClinicalTrials.gov NCT06234007: https://clinicaltrials.gov/study/NCT06234007

## Connected records

- cancers: [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [IMRT / IGRT (modern external beam)](https://onco.cc/technologies/imrt-igrt/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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