# CtDNA in Adjuvant Chemotherapy of Stage III Colon Cancer (REVISE Trial)

Source: https://onco.cc/trials/nct06242418/  
OnCo record `nct06242418` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of FOLFOXIRI and cAPOX (capecitabine, oxaliplatin) in colorectal cancer, run by West China Hospital, now recruiting.

## Summary

CtDNA in Adjuvant Chemotherapy of Stage III Colon Cancer (REVISE Trial) is a phase 2, randomised interventional study registered as NCT06242418 by West China Hospital, with a registry enrolment figure of 60 participants, started 2024-03-25 and due to reach its primary completion in 2025-12-31. Interventions recorded: FOLFOXIRI; XELOX. Conditions listed: Colon Cancer. Primary outcome: change in value of ctDNA concentration. Colorectal eligibility wording from the registry: "Tumor located in the colon (the distance from the lower margin of the tumor to the anus is greater than 12 cm)". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: REVISE
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06242418
- Phase: 2
- Setting: Value of CtDNA in Surveillance of Adjuvant Chemosensitivity and Regimen Adjustment in Stage III Colon Cancer: a Phase II Randomized Controlled Trial (REVISE Trial)
- Sponsor: West China Hospital
- Enrolled: 60

## Sources

- ClinicalTrials.gov NCT06242418: https://clinicaltrials.gov/study/NCT06242418

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [MRD / molecular residual disease testing](https://onco.cc/technologies/mrd-testing/), [Platinum agents](https://onco.cc/technologies/platinum/), [Topoisomerase-I inhibitors (and ADC payloads)](https://onco.cc/technologies/topoisomerase-inhibitors/)
- drugs: [CAPOX (capecitabine, oxaliplatin)](https://onco.cc/drugs/capox/), [FOLFOXIRI (5-FU, leucovorin, oxaliplatin, irinotecan)](https://onco.cc/drugs/folfoxiri/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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