# Sacituzumab Govitecan in Metastatic Colorectal Cancer

Source: https://onco.cc/trials/nct06243393/  
OnCo record `nct06243393` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2/3 trial of sacituzumab govitecan in colorectal cancer, run by University Hospital Heidelberg, now recruiting.

## Summary

Sacituzumab Govitecan in Metastatic Colorectal Cancer is a phase 2/3, randomised interventional study registered as NCT06243393 by University Hospital Heidelberg, with a registry enrolment figure of 80 participants, started 2024-04-19 and due to reach its primary completion in 2028-08-01. Interventions recorded: Sacituzumab Govitecan (SG); Physicians Choice (PhC).. Conditions listed: Metastatic Colorectal Cancer. Primary outcome: Progression Free Survival (PFS). Colorectal eligibility wording from the registry: "Permanent sterilization methods include hysterectomy, bilateral salpingectomy and bilateral oophorectomy". Sites: Germany. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: TROPHIT1
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06243393
- Phase: 2/3
- Setting: A Randomized, Open Label, Multicenter Phase II/III Trial of Sacituzumab Govitecan Compared to Standard of Care in Metastatic, Refractory Colorectal Cancer Patients
- Sponsor: University Hospital Heidelberg
- Enrolled: 80

## Sources

- ClinicalTrials.gov NCT06243393: https://clinicaltrials.gov/study/NCT06243393

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Antibody-drug conjugate (ADC)](https://onco.cc/technologies/adc/)
- drugs: [Sacituzumab govitecan](https://onco.cc/drugs/sacituzumab-govitecan/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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