# Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer

Source: https://onco.cc/trials/nct06260033/  
OnCo record `nct06260033` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Fluoroestradiol F-18 in Breast cancer, run by City of Hope Medical Center, now recruiting.

## Summary

Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer is a phase 2 interventional study registered as NCT06260033 by City of Hope Medical Center, with 18 participants planned, started 2024-07-23 and due to reach its primary completion in 2026-10-29. Interventions recorded: Biospecimen Collection, Bone Scan, Computed Tomography, F-18 16 Alpha-Fluoroestradiol, Positron Emission Tomography, Questionnaire Administration, Stereotactic Body Radiation Therapy. Conditions recorded: Anatomic Stage IV Breast Cancer AJCC v8, Estrogen Receptor-Positive Breast Carcinoma, Metastatic Breast Carcinoma.

Linked to the drug Fluoroestradiol F-18 because the registry names it among its interventions and Breast cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT06260033
- Phase: 2
- Setting: A Phase II Trial of Stereotactic Body Radiation Therapy and Fluoroestradiol Positron Emission Tomography in Patients With Oligoprogressive Estrogen Receptor Positive Metastatic Breast Cancer
- Sponsor: City of Hope Medical Center
- Enrolled: 18

## Sources

- ClinicalTrials.gov NCT06260033: https://clinicaltrials.gov/study/NCT06260033

## Connected records

- cancers: [Breast cancer (all types)](https://onco.cc/cancers/breast-cancer/)
- drugs: [Fluoroestradiol F-18 (FES PET)](https://onco.cc/drugs/fluoroestradiol-f18/)

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