# Personalising and Refining Neo-adjuvant Chemotherapy in Locally Advanced but Resecable Colon Cancer in the Elderly of 70 Years Old or More

Source: https://onco.cc/trials/nct06293625/  
OnCo record `nct06293625` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of fOLFOX (5-FU, leucovorin, oxaliplatin) in colorectal cancer, run by Centre Hospitalier Universitaire Dijon, now recruiting.

## Summary

Personalising and Refining Neo-adjuvant Chemotherapy in Locally Advanced but Resecable Colon Cancer in the Elderly of 70 Years Old or More is a phase 3, randomised interventional study registered as NCT06293625 by Centre Hospitalier Universitaire Dijon, with a registry enrolment figure of 150 participants, started 2024-06-07 and due to reach its primary completion in 2032-06. Interventions recorded: Folfox; Surgery. Conditions listed: Colon Cancer. Primary outcome: DFS (disease Free Survival). Colorectal eligibility wording from the registry: "* Biopsy-confirmed adenocarcinoma of the colon (or upper rectum if too high for radiotherapy), high-grade dysplasia is not acceptable ,". Sites: France. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Also known as: FOxTROT2France
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06293625
- Phase: 3
- Setting: Personalising and Refining Neo-adjuvant Chemotherapy in Locally Advanced but Resecable Colon Cancer in the Elderly of 70 Years Old or More Phase III Multicentric Open-label Randomized Controlled Trial
- Sponsor: Centre Hospitalier Universitaire Dijon
- Enrolled: 150

## Sources

- ClinicalTrials.gov NCT06293625: https://clinicaltrials.gov/study/NCT06293625

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [FOLFOX (5-FU, leucovorin, oxaliplatin)](https://onco.cc/drugs/folfox/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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