# Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurre

Source: https://onco.cc/trials/nct06307548/  
OnCo record `nct06307548` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial in colorectal cancer, run by Roswell Park Cancer Institute, now recruiting.

## Summary

Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer is a phase 1/2, interventional study registered as NCT06307548 by Roswell Park Cancer Institute, with a registry enrolment figure of 21 participants, started 2024-07-30 and due to reach its primary completion in 2027-06-01. Interventions recorded: Aminolevulinic Acid; Biospecimen Collection; Computed Tomography; Fluorescence-Guided Surgery; Magnetic Resonance Imaging; Photodynamic Therapy; Surgical Procedure. Conditions listed: Locally Advanced Colorectal Carcinoma; Recurrent Colorectal Carcinoma; Stage III Colorectal Cancer. Primary outcome: Accuracy of the fluorescence imaging (Phase I); Incidence of adverse events (Phase I); Evidence of disease (Phase II). Colorectal eligibility wording from the registry: "* Patients with locally advanced or recurrent colorectal cancer undergoing surgery". Sites: United States. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06307548
- Phase: 1/2
- Setting: Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Loco-Regionally Advanced or Recurrent Colorectal Cancer Undergoing Surgery - Phase I/II
- Sponsor: Roswell Park Cancer Institute
- Enrolled: 21

## Sources

- ClinicalTrials.gov NCT06307548: https://clinicaltrials.gov/study/NCT06307548

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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