# Efficacy and Safety of JMT101 Combined Wth Docetaxel / HB1801 in Patients With Squamous Cell Non-Small Cell Lung Cancer

Source: https://onco.cc/trials/nct06319313/  
OnCo record `nct06319313` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2/3 trial of JMT101, docetaxel and HB1801 in lung cancer, run by Shanghai JMT-Bio Inc., not yet recruiting.

## Summary

Efficacy and Safety of JMT101 Combined Wth Docetaxel / HB1801 in Patients With Squamous Cell Non-Small Cell Lung Cancer is a phase 2/3, randomised interventional study registered as NCT06319313 by Shanghai JMT-Bio Inc., with a registry enrolment figure of 534 participants, started 2024-05-01 and due to reach its primary completion in 2026-07-01. Interventions recorded: JMT101; docetaxel; HB1801. Conditions listed: Squamous Cell Non-small Cell Lung Cancer. Primary outcome: Overall response rate (ORR); Overall Survival (OS); Incidence and severity of adverse events (AE) and serious adverse events (SAE). Lung eligibility wording from the registry: "Pathological diagnosis as sqNSCLC, with EGFR highly expressed, without other driver genes". No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-25
- Tags: ctgov-ingest; lung-deep-dive
- Registry id: NCT06319313
- Phase: 2/3
- Setting: A Randomized, Controlled, Open-label Phase II/III Study of The Safety, Tolerability and Efficacy of JMT101 Combined With Docetaxel / HB1801 in Patients With sqNSCLC
- Sponsor: Shanghai JMT-Bio Inc.
- Enrolled: 534

## Sources

- ClinicalTrials.gov NCT06319313: https://clinicaltrials.gov/study/NCT06319313

## Connected records

- cancers: [Squamous cell carcinoma of the lung](https://onco.cc/cancers/lung-squamous-cell-carcinoma/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Docetaxel](https://onco.cc/drugs/docetaxel/), [HB1801](https://onco.cc/drugs/hb1801/), [JMT101](https://onco.cc/drugs/jmt101/)
- terms: [Lung cancer trials open today (registry snapshot)](https://onco.cc/terms/lung-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct06319313.json