# Phase II Study of Irinotecan Liposomes in First-line Treatment of Metastatic Colorectal Cancer

Source: https://onco.cc/trials/nct06341296/  
OnCo record `nct06341296` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of fluorouracil (5-FU), leucovorin (folinic acid) and bevacizumab (glioblastoma use) in colorectal cancer, run by West China Hospital, now recruiting.

## Summary

Phase II Study of Irinotecan Liposomes in First-line Treatment of Metastatic Colorectal Cancer is a phase 2, interventional study registered as NCT06341296 by West China Hospital, with a registry enrolment figure of 86 participants, started 2024-06-30 and due to reach its primary completion in 2026-04. Interventions recorded: Irinotecan Liposome; 5-FU; LV; Bevacizumab. Conditions listed: Metastatic Colorectal Cancer. Primary outcome: Objective response rate. Colorectal eligibility wording from the registry: "* Histopathologically confirmed patient with an inoperable metastatic colorectal adenocarcinoma". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; colorectal-deep-dive
- Registry id: NCT06341296
- Phase: 2
- Setting: Phase II Study of Irinotecan Liposomes Combined With 5-FU/LV+ Bevacizumab in First-line Treatment of Metastatic Colorectal Cancer
- Sponsor: West China Hospital
- Enrolled: 86

## Sources

- ClinicalTrials.gov NCT06341296: https://clinicaltrials.gov/study/NCT06341296

## Connected records

- cancers: [Colon cancer (adenocarcinoma of the colon)](https://onco.cc/cancers/colon-cancer/), [Rectal cancer](https://onco.cc/cancers/rectal-cancer/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Bevacizumab (glioblastoma use)](https://onco.cc/drugs/bevacizumab-glioma/), [Fluorouracil (5-FU)](https://onco.cc/drugs/fluorouracil/), [Leucovorin (folinic acid)](https://onco.cc/drugs/leucovorin/)
- terms: [Colorectal cancer trials open today (registry snapshot)](https://onco.cc/terms/colorectal-trials-open-today/)

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