# Intratumoral INT230-6 Followed by Neoadjuvant Immuno-chemotherapy in Patients With Early TNBC. INVINCIBLE-4-SAKK

Source: https://onco.cc/trials/nct06358573/  
OnCo record `nct06358573` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of INT230-6 in triple-negative breast cancer, run by Swiss Cancer Institute, now recruiting.

## Summary

Intratumoral INT230-6 Followed by Neoadjuvant Immuno-chemotherapy in Patients With Early TNBC. INVINCIBLE-4-SAKK is a phase 2, randomised interventional study registered as NCT06358573 by Swiss Cancer Institute, with a registry enrolment figure of 61 participants, started 2024-10-24 and due to reach its primary completion in 2028-10. Interventions recorded: INT230-6; neoadjuvant immuno-chemotherapy. Conditions listed: Triple-negative Breast Cancer; TNBC - Triple-Negative Breast Cancer. Triple-negative eligibility wording from the registry: "* Newly histologically diagnosed, previously untreated locally advanced non-metastatic TNBC as defined by the most recent American Society of Clinical Oncology (ASCO) / College of American Pathologist (CAP) guidelines". Sites: France, Switzerland. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-24
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT06358573
- Phase: 2
- Setting: Intratumoral INT230-6 Followed by Neoadjuvant Immuno-chemotherapy in Patients With Early Triple-negative Breast Cancer (TNBC). An Open-label Randomized Two-cohort Phase 2 Clinical Trial. INVINCIBLE-4-SAKK
- Sponsor: Swiss Cancer Institute
- Enrolled: 61

## Sources

- ClinicalTrials.gov NCT06358573: https://clinicaltrials.gov/study/NCT06358573

## Connected records

- cancers: [Early triple-negative breast cancer](https://onco.cc/cancers/tnbc-early/), [Metastatic triple-negative breast cancer](https://onco.cc/cancers/tnbc-metastatic/)
- drugs: [INT230-6](https://onco.cc/drugs/int230-6/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)

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