# JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

Source: https://onco.cc/trials/nct06386146/  
OnCo record `nct06386146` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 1/2 trial of JAB-30355 in advanced solid tumours, run by Jacobio Pharmaceuticals Co., Ltd., now recruiting.

## Summary

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation is a phase 1/2 interventional study registered as NCT06386146 by Jacobio Pharmaceuticals Co., Ltd., with 144 participants planned, started 2024-07-24 and due to reach its primary completion in 2027-01. Interventions recorded: JAB-30355.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-09-16
- Tags: pipeline; ctgov-ingest
- Registry id: NCT06386146
- Phase: 1/2
- Setting: A Phase 1/2a, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Evidence of Antitumor Activity of JAB-30355 in Adult Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation
- Sponsor: Jacobio Pharmaceuticals Co., Ltd.
- Enrolled: 144

## Sources

- ClinicalTrials.gov NCT06386146: https://clinicaltrials.gov/study/NCT06386146

## Connected records

- cancers: [Metastatic cancer (cancer that has spread)](https://onco.cc/cancers/metastatic-cancer/)
- companies: [Jacobio Pharmaceuticals](https://onco.cc/companies/jacobio-pharmaceuticals/)

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