# QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer

Source: https://onco.cc/trials/nct06404736/  
OnCo record `nct06404736` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of nab-paclitaxel and carboplatin in triple-negative breast cancer, run by Fudan University, not yet recruiting.

## Summary

QL1706 Plus Chemotherapy as Neoadjuvant Therapy in Early High-Risk TNBC Breast Cancer is a phase 2, interventional study registered as NCT06404736 by Fudan University, with a registry enrolment figure of 73 participants, started 2024-05-07 and due to reach its primary completion in 2025-11-07. Interventions recorded: Bispecific antibody (bsAb) targeting PD-1 and CLTA-4; Albumin-bound paclitaxel; Carboplatin. Conditions listed: Early Breast Cancer; Neoadjuvant Therapy; TNBC, Triple Negative Breast Cancer. Triple-negative eligibility wording from the registry: "According to the definition of the latest ASCO/CAP guidelines, histopathologically confirmed TNBC breast cancer, histological grade II, TNM stage T1cN1-cN2 or T2-T4, cN0-cN2;". Sites: China. No results are recorded here; the registry entry is the source.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-09-24
- Also known as: QUEEN-Dream
- Tags: ctgov-ingest; tnbc-deep-dive
- Registry id: NCT06404736
- Phase: 2
- Setting: A Phase II Study of Neoadjuvant QL1706 Plus Chemotherapy in Participants With High-Risk TNBC Early-Stage Breast Cancer (QUEEN-Dream)
- Sponsor: Fudan University
- Enrolled: 73

## Sources

- ClinicalTrials.gov NCT06404736: https://clinicaltrials.gov/study/NCT06404736

## Connected records

- cancers: [Early triple-negative breast cancer](https://onco.cc/cancers/tnbc-early/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/), [Platinum agents](https://onco.cc/technologies/platinum/)
- drugs: [Carboplatin](https://onco.cc/drugs/carboplatin/), [Nab-paclitaxel](https://onco.cc/drugs/nab-paclitaxel/)
- terms: [Triple-negative breast cancer trials open today (registry snapshot and UK sites)](https://onco.cc/terms/tnbc-trials-open-today/)

---
JSON: https://onco.cc/api/v1/entities/nct06404736.json